What is a clinical trial?
Clinical trials are medical research studies involving patient volunteers that are carried out to find better ways to prevent, diagnose or treat disease. They provide crucial evidence that diagnostic tests or treatments are safe and effective. Whether the results are positive or negative, these studies help to answer important questions - both for people with heart or circulatory diseases, and the clinicians providing their care.
Here we highlight some of the more recent clinical trials supported by the BHF.
Every year, thousands of people in the UK present with a suspected heart attack - but it is not always easy to confirm the diagnosis. The High STEACS trial investigated whether a test that can detect tiny amounts of a protein called troponin in the blood could help improve heart attack diagnosis and treatment.
Can aspirin and fish oil supplements protect people with diabetes from heart and circulatory disease?
Having diabetes increases the risk of having a heart attack or stroke. The ASCEND trial asked whether a daily aspirin tablet and/or a fish oil capsule could help to prevent these conditions in people with diabetes.
Cardiovascular events – such as heart attacks - are the leading cause of death among on-duty firefighters. The BHF funded the FIREPROOF study to learn why.
Medication to treat high blood pressure can decrease the risk of having a heart attack or stroke – but doctors were unsure if it was safe and beneficial to prescribe these medications to people over 80. The HYVET trial, which was part-funded by the BHF, aimed to find out.
Many people who go to hospital experiencing chest pain or other symptoms of a heart attack have a partial blockage or narrowing of the coronary arteries – called an ‘NSTEMI’ heart attack. RITA3 examined the best way of treating people experiencing this type of heart attack.
Dilated cardiomyopathy (DCM) is a disease of the heart muscle, which can cause heart failure. In some people with DCM, heart failure treatment can normalise heart function and resolve symptoms, but does this mean that their doctors can stop prescribing them heart failure drugs? The team behind the TRED-HF trial set out to find out the answer.